About St Mary of the Annunciation Cathedral
St Mary of the Annunciation Cathedral is a Catholic Cathedral in Cape Girardeau, Missouri located at 615 William St, Cape Girardeau, MO 63703. St Mary of the Annunciation Cathedral was founded in 1869. As of April 2026, St Mary of the Annunciation Cathedral holds a 4.6-star rating across 67 Google reviews. The St Mary of the Annunciation Cathedral parish office answers at +15733359347.
he Cathedral of St. Mary of the Annunciation, also known as St. Mary's Cathedral, is a Catholic cathedral in Cape Girardeau, Missouri, United States. Along with St. Agnes Cathedral in Springfield, Missouri it is the seat of the Diocese of Springfield-Cape Girardeau.
Patron saint of St Mary of the Annunciation Cathedral
Mary (the Virgin Mary)
Feast day: Aug 15 (Assumption)
Other parishes named after Saint Mary
5 other churches named in honor of Saint Mary are indexed in Churches List. The most-reviewed of those appear below.
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Catholic · Phoenix, AZ
St. Mary
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Catholic · Natchez, MS
St. Mary Basilica
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Catholic · Chicago, IL
Saint Mary of the Angels Church
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Catholic · Chicago, IL
St. Mary of the Lake
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Catholic · Los Angeles, CA
St. Mary
Cathedral of St. Mary of the Annunciation (Cape Girardeau, Missouri)
The Cathedral of St. Mary of the Annunciation, also known as St. Mary's Cathedral, is a Catholic cathedral in Cape Girardeau, Missouri, United States. Along with St. Agnes Cathedral in Springfield, Missouri it is the seat of the Diocese of Springfield-Cape Girardeau.
Where is St Mary of the Annunciation Cathedral located?
St Mary of the Annunciation Cathedral is located at 615 William St, Cape Girardeau, MO 63703. The building sits at coordinates 37.30083, -89.52712, placing it in Cape Girardeau, MO 63703.
Location is approximate — drawn from the public street address.
- Public parking 538 ft
- Public parking 554 ft
- Public parking 928 ft
- Public parking 1060 ft
Nearby places drawn from OpenStreetMap, Apr 23, 2026.
The neighborhood around St Mary of the Annunciation Cathedral
The ZIP code 63703 area around St Mary of the Annunciation Cathedral is home to 8,855 residents with a median household income of $36,992 and a median age of 40.7 years, according to the US Census Bureau's 2022 American Community Survey 5-year estimates.
US Census Bureau, American Community Survey 2022 five-year estimates.
What to expect at a service at St Mary of the Annunciation Cathedral
Roman Catholic parishes follow a structured liturgy called the Mass, celebrated worldwide in the same order.
- Mass lasts about an hour and includes Scripture readings, a homily, hymns, and Holy Communion.
- Visitors are welcome. Only baptized Catholics in good standing receive Communion; others come forward with arms crossed for a blessing.
- Dress is modest but not formal — business casual is typical for Sunday Mass.
Generalized notes for first-time visitors. Individual parishes vary — when in doubt, ask a greeter at the door.
Churches sharing the architectural tradition of St Mary of the Annunciation Cathedral
5 other US churches in the Romanesque Revival architecture tradition are indexed in Churches List.
- Sacred Heart Church Tampa, FL · est. 1905
- Sacred Heart Tampa, FL · est. 1905
- St John Neumann Shrine Philadelphia, PA · est. 1847
- Saint Joseph Catholic Church Tampa, FL · est. 1905
- Saint John Catholic Church St. Petersburg, FL · est. 1905
Churches founded the same year as St Mary of the Annunciation Cathedral
4 other churches with a documented founding year of 1869 are indexed in Churches List.
- Chicago First Baptist Congregational Chicago, IL
- Lincoln Park Baptist Church Newton, MA
- Saint John Baptist Church Reading, PA
- Bethel United Methodist Church Indianapolis, IN
St Mary of the Annunciation Cathedral by the numbers
Questions and answers about St Mary of the Annunciation Cathedral
- What denomination is St Mary of the Annunciation Cathedral?
- This parish is part of the Catholic tradition.
- Where is St Mary of the Annunciation Cathedral located?
- The parish is located at 615 William St, Cape Girardeau, MO 63703.
- When was St Mary of the Annunciation Cathedral founded?
- Founded in 1869.
- Who is the patron saint of St Mary of the Annunciation Cathedral?
- Saint Mary (Mary (the Virgin Mary)). Feast day: Aug 15 (Assumption).
- How do visitors rate St Mary of the Annunciation Cathedral?
- 4.6 out of 5 stars, based on 67 Google reviews.
- What is the architecture of St Mary of the Annunciation Cathedral?
- St Mary of the Annunciation Cathedral is a Romanesque Revival architecture building.
- Is St Mary of the Annunciation Cathedral the official parish listing?
- This listing is compiled from public Google Business data and has not yet been claimed by the parish. If you represent St Mary of the Annunciation Cathedral, you can claim the listing to edit hours, photos, and announcements.
Photographs of St Mary of the Annunciation Cathedral
Photographs via Wikimedia Commons. Click through for author and licence.
Visitor notes about St Mary of the Annunciation Cathedral
Short, text-only reflections left by visitors. No ratings, no photographs — by editorial policy.
No notes yet for this parish. Visitor notes are coming soon — for now, write to editors@churcheslist.com and we'll post your reflection by hand.